77 Research Compounds

Peptide Research
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A comprehensive scientific database of peptide and peptide-adjacent compounds. Explore detailed research profiles, mechanisms of action, clinical evidence, and regulatory status.

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Latest Research Studies

Recently published peptide research from peer-reviewed journals

Healing & Recovery
2026 Apr 09

Cardiac targeting extracellular vesicles combined with quercetin co-delivery system enhances the therapeutic efficacy of myocardial infarction.

Scientists have developed a new way to treat heart attacks using tiny natural packages from human blood, called extracellular vesicles, combined with a plant compound called quercetin. They modified these packages with a special peptide to target the damaged heart, delivering both substances to reduce inflammation, fight harmful molecules, and prevent cell death. This combined approach shows promise for repairing heart damage more effectively than current treatments.

Biomaterials advances
PubMed
Neuroprotection & Cognitive
2026 Apr 15

The pituitary adenylate cyclase-activating polypeptide receptor and its splice variants: Unique roles in affective and motivated behavior.

This research explores how a brain chemical called PACAP and its specific receptors, particularly different versions of the PAC1 receptor, influence our stress responses, emotions, and motivated behaviors, especially drug addiction. The study suggests that these receptor variants might play distinct roles in how the brain reacts to stress and drug use, potentially changing how PACAP affects drug-seeking behavior over time. Understanding these differences could lead to new treatments for addiction.

Journal of neuroendocrinology
PubMed
Therapeutic Peptides
2026 Apr 12

AI-assisted transformation of PD-L1 inhibitory peptides into small molecules using amino acid mapping descriptor and activity improvement through structure-based drug design.

This research developed a new method using artificial intelligence to transform a peptide drug into a smaller, more effective drug molecule. This new approach helps create drugs that can block specific protein interactions, like those involving PD-L1, which is important for treating diseases. The study successfully created small molecules with improved properties, demonstrating a promising way to discover new therapies.

Bioorganic & medicinal chemistry letters
PubMed
Cancer Research
2026 Apr 15

Risk Factors and Comparative Safety of Anti-PD-1 Combination Therapies in Advanced Melanoma: A Nationwide Real-World Cohort Study From China.

This study investigated the safety and side effects of different drug combinations used to treat advanced melanoma, a type of skin cancer, in China. Researchers found that while many anti-PD-1 combination therapies were generally safe, a specific triple therapy combining PD-1 inhibitors with interferon Alfa-1b and TKI drugs led to severe side effects and is not recommended. The study helps doctors understand which treatments are safer for patients.

Cancer medicine
PubMed
77
Total Compounds
13 per entry
Research Sections
Preclinical to Approved
Evidence Tracked
1,000+
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